Title : Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation.

Pub. Date : 2017 Nov

PMID : 28751023






1 Functional Relationships(s)
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1 Collectively, these results suggest that LYCAT is a negative regulator of TGF-beta-induced lung fibroblast differentiation by modulation of mitochondrial superoxide and NOX4 dependent H2O2 generation, and this may serve as a potential therapeutic target for human lung fibrosis. Hydrogen Peroxide transforming growth factor beta 1 Homo sapiens