Title : SIRT-1 regulates TGF-β-induced dermal fibroblast migration via modulation of Cyr61 expression.

Pub. Date : 2018 May

PMID : 28750181






3 Functional Relationships(s)
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1 Treatment with resveratrol (RSV), a SIRT1 agonist, or overexpression of SIRT1 also promoted the expression Cyr61 in human dermal fibroblasts, whereas the inhibition of SIRT1 activity by nicotinamide or knockdown of SIRT1 decreased the level of Cyr61, as well as TGF-beta or RSV-induced Cyr61 expression. Niacinamide sirtuin 1 Homo sapiens
2 Treatment with resveratrol (RSV), a SIRT1 agonist, or overexpression of SIRT1 also promoted the expression Cyr61 in human dermal fibroblasts, whereas the inhibition of SIRT1 activity by nicotinamide or knockdown of SIRT1 decreased the level of Cyr61, as well as TGF-beta or RSV-induced Cyr61 expression. Niacinamide sirtuin 1 Homo sapiens
3 Treatment with resveratrol (RSV), a SIRT1 agonist, or overexpression of SIRT1 also promoted the expression Cyr61 in human dermal fibroblasts, whereas the inhibition of SIRT1 activity by nicotinamide or knockdown of SIRT1 decreased the level of Cyr61, as well as TGF-beta or RSV-induced Cyr61 expression. Niacinamide sirtuin 1 Homo sapiens