Title : CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA.

Pub. Date : 2018

PMID : 28749203






1 Functional Relationships(s)
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1 R175H p53 expression was rescued by addition of proteasome inhibitor MG132 to CB002, suggesting a role for ubiquitin-mediated degradation of the mutant protein. benzyloxycarbonylleucyl-leucyl-leucine aldehyde tumor protein p53 Homo sapiens