Pub. Date : 1986 Jun
PMID : 2874568
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The effects of prior treatment with cysteamine, a drug which appears to deplete selectively the neuropeptide somatostatin, on apomorphine-induced stereotypy and amphetamine-induced locomotor activity and conditioned place preferences were investigated. | Cysteamine | somatostatin | Homo sapiens |
2 | Twelve hours following systemic cysteamine injections apomorphine-induced stereotypy was attenuated and striatal somatostatin levels were reduced by half. | Cysteamine | somatostatin | Homo sapiens |
3 | Direct injections of cysteamine into the nucleus accumbens also decreased the locomotor response to amphetamine, and produced a local reduction in somatostatin levels in the accumbens. | Cysteamine | somatostatin | Homo sapiens |
4 | Furthermore, it is evident from these results that cysteamine is an important tool with which to study the central actions of somatostatin. | Cysteamine | somatostatin | Homo sapiens |