Title : Raf-1/CK2 and RhoA/ROCK signaling promote TNF-α-mediated endothelial apoptosis via regulating vimentin cytoskeleton.

Pub. Date : 2017 Aug 15

PMID : 28743511






1 Functional Relationships(s)
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1 Suppression of Raf-1 or CK2 by its inhibitor (GW5074 or TBB) blocked vimentin phosphorylation, remodeling and endothelial apoptosis, and preserved cell viability in TNF-alpha-induced HUVECs. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens