Title : Serum 25-hydroxyvitamin D concentrations are associated with nuclear factor kappa-B activity but not with inflammatory markers in healthy normoglycemic adults.

Pub. Date : 2018 Mar

PMID : 28732679






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Vitamin D has been reported to have anti-inflammatory properties in in vitro and animal studies, which are thought to occur via inhibition of the nuclear factor kappa-B (NFkappaB) pathway. Vitamin D nuclear factor kappa B subunit 1 Homo sapiens
2 Vitamin D has been reported to have anti-inflammatory properties in in vitro and animal studies, which are thought to occur via inhibition of the nuclear factor kappa-B (NFkappaB) pathway. Vitamin D nuclear factor kappa B subunit 1 Homo sapiens
3 However, the association between vitamin D and in vivo NFkappaB activity in humans has not previously been reported. Vitamin D nuclear factor kappa B subunit 1 Homo sapiens
4 Although in-vitro studies suggest that vitamin D inhibits NFkappaB activity, our novel cross-sectional data from a cohort of healthy individuals suggest that vitamin D may regulate rather than inhibit the NFkappaB pathway. Vitamin D nuclear factor kappa B subunit 1 Homo sapiens
5 Although in-vitro studies suggest that vitamin D inhibits NFkappaB activity, our novel cross-sectional data from a cohort of healthy individuals suggest that vitamin D may regulate rather than inhibit the NFkappaB pathway. Vitamin D nuclear factor kappa B subunit 1 Homo sapiens
6 Large-scale intervention and mechanistic studies are needed to further investigate the effects of vitamin D on NFkappaB activity in vivo in humans. Vitamin D nuclear factor kappa B subunit 1 Homo sapiens