Pub. Date : 2018 Mar
PMID : 28732679
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Vitamin D has been reported to have anti-inflammatory properties in in vitro and animal studies, which are thought to occur via inhibition of the nuclear factor kappa-B (NFkappaB) pathway. | Vitamin D | nuclear factor kappa B subunit 1 | Homo sapiens |
2 | Vitamin D has been reported to have anti-inflammatory properties in in vitro and animal studies, which are thought to occur via inhibition of the nuclear factor kappa-B (NFkappaB) pathway. | Vitamin D | nuclear factor kappa B subunit 1 | Homo sapiens |
3 | However, the association between vitamin D and in vivo NFkappaB activity in humans has not previously been reported. | Vitamin D | nuclear factor kappa B subunit 1 | Homo sapiens |
4 | Although in-vitro studies suggest that vitamin D inhibits NFkappaB activity, our novel cross-sectional data from a cohort of healthy individuals suggest that vitamin D may regulate rather than inhibit the NFkappaB pathway. | Vitamin D | nuclear factor kappa B subunit 1 | Homo sapiens |
5 | Although in-vitro studies suggest that vitamin D inhibits NFkappaB activity, our novel cross-sectional data from a cohort of healthy individuals suggest that vitamin D may regulate rather than inhibit the NFkappaB pathway. | Vitamin D | nuclear factor kappa B subunit 1 | Homo sapiens |
6 | Large-scale intervention and mechanistic studies are needed to further investigate the effects of vitamin D on NFkappaB activity in vivo in humans. | Vitamin D | nuclear factor kappa B subunit 1 | Homo sapiens |