Title : The effect of antidepressants on ethylmorphine and imipramine N-demethylation in rat liver microsomes.

Pub. Date : 1986 May

PMID : 2872321






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Prolonged administration of desipramine and citalopram, but not amitriptyline, elevated the microsomal level of cytochrome P-450 and accelerated the rate of ethylmorphine demethylation. Desipramine cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus