Title : Label-Free Homogeneous Electroanalytical Platform for Pesticide Detection Based on Acetylcholinesterase-Mediated DNA Conformational Switch Integrated with Rolling Circle Amplification.

Pub. Date : 2017 Apr 28

PMID : 28723196






2 Functional Relationships(s)
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1 When target pesticides were present, AChE activity was inhibited and could not trigger the following DNA conformational change and the RCA reaction, which results in numerous methylene blue (MB) molecules in a free state, generating a strong electrochemical response. Methylene Blue acetylcholinesterase (Cartwright blood group) Homo sapiens
2 When target pesticides were present, AChE activity was inhibited and could not trigger the following DNA conformational change and the RCA reaction, which results in numerous methylene blue (MB) molecules in a free state, generating a strong electrochemical response. Methylene Blue acetylcholinesterase (Cartwright blood group) Homo sapiens