Title : [Low-molecular-weight regulators of biogenic polyamine metabolism affect cytokine production and expression of hepatitis ะก virus proteins in Huh7.5 human hepatocarcinoma cells].

Pub. Date : 2017 May-Jun

PMID : 28707668






1 Functional Relationships(s)
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1 It has been demonstrated that, in cells transfected with HCV genes, DFMO reduces the production of three out of four tested cytokines, namely, TNF-alpha and TGF-beta in cells that express HCV core, E1E2, NS3, NS5A, and NS5B proteins, and IL-1beta in the cells that express HCV core, E1E2, and NS3 proteins. Eflornithine interleukin 1 beta Homo sapiens