Pub. Date : 2017 Sep
PMID : 28696229
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of our study was to evaluate rilpivirine interactions with abacavir and lamivudine on selected ABC and SLC transporters in vitro and assess its importance for pharmacokinetics in vivo Using accumulation assays in MDCK cells overexpressing selected ABC or SLC drug transporters, we revealed rilpivirine as a potent inhibitor of MDR1 and BCRP, but not MRP2, OCT1, OCT2, or MATE1. | abacavir | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |