Title : Aspirin disrupts the mTOR-Raptor complex and potentiates the anti-cancer activities of sorafenib via mTORC1 inhibition.

Pub. Date : 2017 Oct 10

PMID : 28687354






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1 Additionally, the combination of aspirin and sorafenib showed synergetic effects via inhibiting mTORC1 signaling and the PI3K/AKT, MAPK/ERK pathways. Sorafenib mitogen-activated protein kinase 1 Homo sapiens