Pub. Date : 2017 Jul 6
PMID : 28684787
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Polysulfide Na2S4 regulates the activation of PTEN/Akt/CREB signaling and cytotoxicity mediated by 1,4-naphthoquinone through formation of sulfur adducts. | 1,4-naphthoquinone | cAMP responsive element binding protein 1 | Mus musculus |
| 2 | 1,4-NQ, at up to 10 microM, increased phosphorylation of Akt and cAMP response element binding protein (CREB). | 1,4-naphthoquinone | cAMP responsive element binding protein 1 | Mus musculus |
| 3 | 1,4-NQ, at up to 10 microM, increased phosphorylation of Akt and cAMP response element binding protein (CREB). | 1,4-naphthoquinone | cAMP responsive element binding protein 1 | Mus musculus |
| 4 | These bell-shaped dose curves for Akt and CREB activation were right-shifted in cells treated with both 1,4-NQ and Na2S4. | 1,4-naphthoquinone | cAMP responsive element binding protein 1 | Mus musculus |