Title : The nuclear factor-erythroid 2-related factor/heme oxygenase-1 axis is critical for the inflammatory features of type 2 diabetes-associated osteoarthritis.

Pub. Date : 2017 Sep 1

PMID : 28684418






1 Functional Relationships(s)
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1 Ex vivo experiments indicated that Nrf-2 and HO-1 expression is reduced in T2DM versus non-T2DM OA cartilage (0.57-fold Nrf-2 and 0.34-fold HO-1), and prostaglandin E2 (PGE2) release was increased in samples with low HO-1 expression. Dinoprostone NFE2 like bZIP transcription factor 2 Homo sapiens