Title : Evidence that activation of P2X7R does not exacerbate neuronal death after optic nerve transection and focal cerebral ischemia in mice.

Pub. Date : 2017 Oct

PMID : 28669743






1 Functional Relationships(s)
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1 These results indicated that inhibition of P2X7R with BBG promoted neuronal survival, not through the activation of survival kinase pathways, but possibly by improved intracellular Ca2+ overload and decreased the levels of Caspase 1, IL-1beta and Bax proteins. coomassie Brilliant Blue caspase 1 Mus musculus