Title : Activities of drug-metabolizing enzymes in isolated gamma-glutamyltranspeptidase positive preneoplastic hepatocytes from carcinogen treated rats.

Pub. Date : 1985 Oct

PMID : 2866028






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cytochrome P-450 dependent metabolism of benzo[a]pyrene, aldrin and ethoxyresorufin was 43-54% lower than in the parent cell suspension, glucuronidation of 3-hydroxybenzo[a]pyrene (3-OH-BP) and hydrolysis of styrene oxide were increased 1.5- and 1.4-fold, respectively. Benzo(a)pyrene cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus