Title : Palmitic Acid-BSA enhances Amyloid-β production through GPR40-mediated dual pathways in neuronal cells: Involvement of the Akt/mTOR/HIF-1α and Akt/NF-κB pathways.

Pub. Date : 2017 Jun 28

PMID : 28659580






4 Functional Relationships(s)
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1 Palmitic Acid-BSA enhances Amyloid-beta production through GPR40-mediated dual pathways in neuronal cells: Involvement of the Akt/mTOR/HIF-1alpha and Akt/NF-kappaB pathways. Palmitic Acid AKT serine/threonine kinase 1 Homo sapiens
2 Palmitic Acid-BSA enhances Amyloid-beta production through GPR40-mediated dual pathways in neuronal cells: Involvement of the Akt/mTOR/HIF-1alpha and Akt/NF-kappaB pathways. Palmitic Acid AKT serine/threonine kinase 1 Homo sapiens
3 In conclusion, these results show that extra-cellular PA coupled with GPR40 induces the expression of APP and BACE1 to facilitate Abeta production via the Akt-mTOR-HIF-1alpha and Akt-NF-kappaB pathways in SK-N-MC cells. Palmitic Acid AKT serine/threonine kinase 1 Homo sapiens
4 In conclusion, these results show that extra-cellular PA coupled with GPR40 induces the expression of APP and BACE1 to facilitate Abeta production via the Akt-mTOR-HIF-1alpha and Akt-NF-kappaB pathways in SK-N-MC cells. Palmitic Acid AKT serine/threonine kinase 1 Homo sapiens