Title : Molecular and physiological properties of tyrosine hydroxylase induced by reserpine in rat adrenal gland.

Pub. Date : 1985 Oct 28

PMID : 2865664






10 Functional Relationships(s)
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1 Molecular and physiological properties of tyrosine hydroxylase induced by reserpine in rat adrenal gland. Reserpine tyrosine hydroxylase Rattus norvegicus
2 Newly synthesized tyrosine hydroxylase (TH) induced by reserpine was compared with the enzyme in control rats in terms of the molecular and physiological properties. Reserpine tyrosine hydroxylase Rattus norvegicus
3 Newly synthesized tyrosine hydroxylase (TH) induced by reserpine was compared with the enzyme in control rats in terms of the molecular and physiological properties. Reserpine tyrosine hydroxylase Rattus norvegicus
4 Furthermore, when TH in the adrenal glands from both control and reserpine-treated rats was purified, both total activity of the enzyme and the enzyme protein content purified from reserpine-treated rats were also about 3-fold higher than those of the control rats. Reserpine tyrosine hydroxylase Rattus norvegicus
5 Furthermore, when TH in the adrenal glands from both control and reserpine-treated rats was purified, both total activity of the enzyme and the enzyme protein content purified from reserpine-treated rats were also about 3-fold higher than those of the control rats. Reserpine tyrosine hydroxylase Rattus norvegicus
6 These results indicate that newly synthesized TH induced by reserpine in rat adrenal gland had similar properties as the enzyme in control rats and that reserpine increased not only the amount of TH molecules but also the in situ activity of TH. Reserpine tyrosine hydroxylase Rattus norvegicus
7 These results indicate that newly synthesized TH induced by reserpine in rat adrenal gland had similar properties as the enzyme in control rats and that reserpine increased not only the amount of TH molecules but also the in situ activity of TH. Reserpine tyrosine hydroxylase Rattus norvegicus
8 These results indicate that newly synthesized TH induced by reserpine in rat adrenal gland had similar properties as the enzyme in control rats and that reserpine increased not only the amount of TH molecules but also the in situ activity of TH. Reserpine tyrosine hydroxylase Rattus norvegicus
9 These results indicate that newly synthesized TH induced by reserpine in rat adrenal gland had similar properties as the enzyme in control rats and that reserpine increased not only the amount of TH molecules but also the in situ activity of TH. Reserpine tyrosine hydroxylase Rattus norvegicus
10 Since reserpine also increases the biosynthesis of tetrahydrobiopterin as demonstrated by Viveros and co-workers, this 6-fold increase in in situ TH activity may depend both upon the 3-fold increase in the amount of enzyme molecules and upon the increase of the physiologically available tetrahydrobiopterin in the adrenal gland. Reserpine tyrosine hydroxylase Rattus norvegicus