Title : Melatonin Suppresses Neuropathic Pain via MT2-Dependent and -Independent Pathways in Dorsal Root Ganglia Neurons of Mice.

Pub. Date : 2017

PMID : 28656058






2 Functional Relationships(s)
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1 Application of Mel or 8MP in cuff-implanted models inhibited the activation of peptidergic neurons and neuro-inflammation in the DRGs by down-regulating c-fos, calcitonin gene-related peptide [CGRP], and tumor necrosis factor-1alpha [TNF-1alpha] and interleukin-1beta [IL-1beta]. Melatonin interleukin 1 beta Mus musculus
2 Application of Mel or 8MP in cuff-implanted models inhibited the activation of peptidergic neurons and neuro-inflammation in the DRGs by down-regulating c-fos, calcitonin gene-related peptide [CGRP], and tumor necrosis factor-1alpha [TNF-1alpha] and interleukin-1beta [IL-1beta]. Melatonin interleukin 1 beta Mus musculus