Title : Acquisition of anoikis resistance promotes alterations in the Ras/ERK and PI3K/Akt signaling pathways and matrix remodeling in endothelial cells.

Pub. Date : 2017 Sep

PMID : 28653224






1 Functional Relationships(s)
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1 Endothelial cells submitted to stressful conditions by blocking adhesion to substrate (anoikis resistance) display an up-regulation of Ras/ERK and PI3k/Akt pathways by high expression of Ras, ERK, PI3K (p110alpha) and Akt (Thr 308). Threonine mitogen-activated protein kinase 1 Homo sapiens