Title : IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells.

Pub. Date : 2017 Oct 1

PMID : 28651331






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 By using cultured granulosa-lutein cells collected from women undergoing in vitro fertilization or intracytoplasmic sperm injection, we found that IL-1beta upregulated steroidogenic acute regulatory protein (StAR) expression and progesterone synthesis in granulosa-lutein cells, which was comparable with luteinizing hormone effect and could be abolished by an IL-1 receptor antagonist. Progesterone steroidogenic acute regulatory protein Homo sapiens