Title : IL-1β Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells.

Pub. Date : 2017 Oct 1

PMID : 28651331






2 Functional Relationships(s)
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1 IL-1beta Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells. Progesterone mitogen-activated protein kinase 3 Homo sapiens
2 Furthermore, IL-1beta activated the extracellular signal-regulated kinase (ERK)1/2 and p38 pathways and inhibition of the ERK1/2 and p38 pathways attenuated the IL-1beta-induced phosphorylation of CREB, StAR expression, and progesterone synthesis in granulosa-lutein cells. Progesterone mitogen-activated protein kinase 3 Homo sapiens