Pub. Date : 2017 Oct 1
PMID : 28651331
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | IL-1beta Upregulates StAR and Progesterone Production Through the ERK1/2- and p38-Mediated CREB Signaling Pathways in Human Granulosa-Lutein Cells. | Progesterone | mitogen-activated protein kinase 3 | Homo sapiens |
2 | Furthermore, IL-1beta activated the extracellular signal-regulated kinase (ERK)1/2 and p38 pathways and inhibition of the ERK1/2 and p38 pathways attenuated the IL-1beta-induced phosphorylation of CREB, StAR expression, and progesterone synthesis in granulosa-lutein cells. | Progesterone | mitogen-activated protein kinase 3 | Homo sapiens |