Title : Influence of cimetidine, sulfinpyrazone, and cigarette smoking on theobromine metabolism in man.

Pub. Date : 1985 Sep-Oct

PMID : 2865110






3 Functional Relationships(s)
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1 When compared with previous data relating to theophylline, the results suggest that theobromine 3-demethylation is mediated by the same form(s) of cytochrome P-450 involved in theophylline demethylation, while a second form(s) of cytochrome P-450 is involved in theobromine 7-demethylation and theophylline 8-hydroxylation. Theophylline cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 When compared with previous data relating to theophylline, the results suggest that theobromine 3-demethylation is mediated by the same form(s) of cytochrome P-450 involved in theophylline demethylation, while a second form(s) of cytochrome P-450 is involved in theobromine 7-demethylation and theophylline 8-hydroxylation. Theophylline cytochrome P450 family 4 subfamily F member 3 Homo sapiens
3 When compared with previous data relating to theophylline, the results suggest that theobromine 3-demethylation is mediated by the same form(s) of cytochrome P-450 involved in theophylline demethylation, while a second form(s) of cytochrome P-450 is involved in theobromine 7-demethylation and theophylline 8-hydroxylation. Theophylline cytochrome P450 family 4 subfamily F member 3 Homo sapiens