Title : Autoregulation of endogenous epinephrine release via presynaptic adrenoceptors in the rat hypothalamic slice.

Pub. Date : 1985 Oct

PMID : 2864433






1 Functional Relationships(s)
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1 Spontaneous and evoked release of epinephrine was markedly reduced, when rats were pretreated with 2,3-dichloro-alpha-methylbenzylamine, an inhibitor of phenylethanolamine N-methyltransferase, the enzyme catalyzing the formation of epinephrine from norepinephrine, 80 mg/kg i.p., before decapitation. Norepinephrine phenylethanolamine-N-methyltransferase Rattus norvegicus