Title : MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect.

Pub. Date : 2017 Jun 23

PMID : 28644127






1 Functional Relationships(s)
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1 These phenotypes are caused by induction of p53 and accumulation of the glycolytic intermediate fructose 6-phosphate, leading to engagement of the hexosamine biosynthetic pathway (HBP), increased O-GlcNAcylation, and p53 stabilization. Hexosamines tumor protein p53 Homo sapiens