Title : Interplay of nutrients and hormones in the regulation of insulin release.

Pub. Date : 1985 Sep

PMID : 2862021






2 Functional Relationships(s)
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1 This poor nutrient-induced insulin release from purified B cells is attributed to their low cAMP levels and is markedly increased after addition of (Bu)2cAMP, of glucagon, or of pancreatic A cells. Cyclic AMP insulin Homo sapiens
2 These results strongly support the concept that the potent in vivo insulin-releasing action of glucose and leucine is not only dependent on their fuel capacity in pancreatic B cells but also on the concurrent cAMP levels in these cells. Cyclic AMP insulin Homo sapiens