Title : Roflupram, a Phosphodiesterase 4 Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells.

Pub. Date : 2017 Nov 15

PMID : 28605578






1 Functional Relationships(s)
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1 We found that both LPS plus ATP and Abeta25-35 enhanced the conversion of pro-caspase-1 to cleaved-caspase-1 and increased the production of mature IL-1beta in BV-2 cells. Adenosine Triphosphate interleukin 1 beta Mus musculus