Title : Extracellular signal-regulated kinase 5 associates with casein kinase II to regulate GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway.

Pub. Date : 2017 Aug

PMID : 28603902






1 Functional Relationships(s)
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1 The CKII inhibitor TBB, similar to the ERK5 inhibitor XMD8-92, specifically restrained PTEN phosphorylation, therefore suppressing Akt phosphorylation in human platelets treated with botrocetin/VWF. 2-ethylhexyl 2,3,4,5-tetrabromobenzoate phosphatase and tensin homolog Homo sapiens