Title : Blunted insula activation reflects increased risk and reward seeking as an interaction of testosterone administration and the MAOA polymorphism.

Pub. Date : 2017 Sep

PMID : 28603901






4 Functional Relationships(s)
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1 Testosterone, a male sex hormone, has been suggested to partly explain mixed findings in males and females when investigating behavioral tendencies associated with the MAOA polymorphism. Testosterone monoamine oxidase A Homo sapiens
2 Moreover, after testosterone administration, MAOA-S carriers were more risk-taking. Testosterone monoamine oxidase A Homo sapiens
3 In the anterior insula, testosterone administration mitigated this effect solely in MAOA-S carriers. Testosterone monoamine oxidase A Homo sapiens
4 While the molecular basis is not well defined so far, our results support the assumption of testosterone as a modulatory factor for previously reported sex differences of behavioral associations with the MAOA-S variant. Testosterone monoamine oxidase A Homo sapiens