Title : JNK/AP-1 activation contributes to tetrandrine resistance in T-cell acute lymphoblastic leukaemia.

Pub. Date : 2017 Aug

PMID : 28603286






2 Functional Relationships(s)
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1 Interestingly, when treated with TET, TET-R Jurkat cells exhibited enhanced AP-1 and NF-kappaB activity, along with upregulation of c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) signaling pathways, whereas the expression of P-gp was not altered. tetrandrine phosphoglycolate phosphatase Homo sapiens
2 Interestingly, when treated with TET, TET-R Jurkat cells exhibited enhanced AP-1 and NF-kappaB activity, along with upregulation of c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) signaling pathways, whereas the expression of P-gp was not altered. tetrandrine phosphoglycolate phosphatase Homo sapiens