Pub. Date : 2017 Jun 12
PMID : 28592027
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Glyburide prevents pulmonary artery smooth muscle cell proliferation and migration via inhibiting NLRP3 activation]. | Glyburide | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Objective: To investigate whether glyburide prevents platelet-derived growth factor (PDGF) induced pulmonary artery smooth muscle cells(PASMCs) proliferation and migration via inhibiting nucleotide binding domain leucine-rich repeat-containing receptors protein 3(NLRP3) inflammasome activation. | Glyburide | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Conclusion: Glyburide could ameliorate PDGF-induced PASMCs proliferation and migration by inhibiting NLRP3 inflammasome activation. | Glyburide | NLR family pyrin domain containing 3 | Homo sapiens |