Title : Chemoenzymatic synthesis of optically active phenolic 3,4-dihydropyridin-2-ones: a way to access enantioenriched 1,4-dihydropyridine and benzodiazepine derivatives.

Pub. Date : 2017 Jun 21

PMID : 28590004






1 Functional Relationships(s)
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1 The enantioenriched 3,4-DHP-2-ones have easily been converted into highly functionalized (R)- and (S)-1,4-dihydropyridines (1,4-DHPs) by means of a Vilsmeier-Haack reaction. 1,4-dihydropyridine dihydropyrimidinase Homo sapiens