Title : Chemoenzymatic synthesis of optically active phenolic 3,4-dihydropyridin-2-ones: a way to access enantioenriched 1,4-dihydropyridine and benzodiazepine derivatives.

Pub. Date : 2017 Jun 21

PMID : 28590004






1 Functional Relationships(s)
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1 Finally, the coupling of the 1,4-DHPs with benzene-1,2-diamine using TFA as an acid promoter provided us the corresponding optically active hybrid 1,5-benzodiazepine-1,4-dihydropyridine (BZD-DHP) derivatives. Trifluoroacetic Acid dihydropyrimidinase Homo sapiens