Pub. Date : 2017 Aug 1
PMID : 28587821
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structural development of 1,2,3,4-tetrahydroisoquinoline-type positive allosteric modulators of prostacyclin receptor (IPPAMs) to improve metabolic stability, and investigation of metabolic fate. | 1,2,3,4-tetrahydroisoquinoline | prostaglandin I2 receptor | Homo sapiens |
| 2 | We synthesized a series of 1,2,3,4-tetrahydroisoquinoline-type positive allosteric modulators of prostacyclin receptor (IPPAMs), aiming to improve the metabolic stability of the previously identified hit compound IPPAM-3 (2). | 1,2,3,4-tetrahydroisoquinoline | prostaglandin I2 receptor | Homo sapiens |