Title : Effectiveness of imatinib mesylate over etoposide in the treatment of sensitive and resistant chronic myeloid leukaemia cells in vitro.

Pub. Date : 2017 Jun

PMID : 28587395






1 Functional Relationships(s)
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1 However, the IC50 for etoposide in sensitive K562 cells was markedly lower than that of K562/ADM cells (50.6+-16.5 and 194+-8.46 microM, respectively), suggesting that the higher expression levels of MDR1 and/or BCL-2 mRNA in resistant cells may be partially responsible for this effect. Etoposide ATP binding cassette subfamily B member 1 Homo sapiens