Pub. Date : 2017 May 25
PMID : 28587082
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | P-gp, a unique ATP-dependent membrane transport protein, is one of those key regulators which are present in the lining of the colon, endothelial cells of the blood brain barrier (BBB), bile duct, adrenal gland, kidney tubules, small intestine, pancreatic ducts and in many other tissues like heart, lungs, spleen, skeletal muscles, etc. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | P-gp inhibitors act by altering intracellular ATP levels which are the source of energy and/or by affecting membrane contours to increase permeability. | Adenosine Triphosphate | ATP binding cassette subfamily B member 1 | Homo sapiens |