Title : Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2α receptors.

Pub. Date : 2017 Jul 21

PMID : 28584054






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ligand occupancy of the AT1R induced distinct conformational changes in FP compared with those driven by PGF2alpha in bioluminescence resonance energy transfer (BRET)-based FP biosensors engineered with Renilla luciferase (RLuc) as an energy donor in the C-tail and fluorescein arsenical hairpin binder (FlAsH)-labeled acceptors at different positions in the intracellular loops. Fluorescein angiotensin II receptor type 1 Homo sapiens