Title : Discovery of a Diaminopyrimidine FLT3 Inhibitor Active against Acute Myeloid Leukemia.

Pub. Date : 2017 May 31

PMID : 28580438






2 Functional Relationships(s)
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1 Profiling of the kinase-binding capabilities of an aminopyrimidine analogue detected in a cellular screen of the St. Jude small-molecule collection led to the identification of a novel series of FMS-like tyrosine kinase 3 (FLT3) inhibitors. 2-aminopyrimidine fms related receptor tyrosine kinase 3 Homo sapiens
2 Profiling of the kinase-binding capabilities of an aminopyrimidine analogue detected in a cellular screen of the St. Jude small-molecule collection led to the identification of a novel series of FMS-like tyrosine kinase 3 (FLT3) inhibitors. 2-aminopyrimidine fms related receptor tyrosine kinase 3 Homo sapiens