Title : Inflammasomes and IL-1 biology in the pathogenesis of allograft dysfunction.

Pub. Date : 2017 Jun 1

PMID : 28569730






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This is followed by signal two, which involves recognition of PAMPs or damage-associated molecular patterns (DAMPs), such as uric acid or ATP, via NLRP3, which leads to caspase-1-dependent cleavage of pro-IL-1beta to active IL-1beta and pyroptosis. Uric Acid NLR family pyrin domain containing 3 Homo sapiens