Title : Central nervous system action of TRH to stimulate gastric function and ulceration.

Pub. Date : 1988

PMID : 2856654






1 Functional Relationships(s)
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1 Intracisternal or intracerebroventricular injection of TRH (0.1-10 micrograms) in rats stimulated the secretion of gastric acid and pepsin secretion, increased gastric mucosal blood flow and gastric contractility and emptying, induced gastric hemorrhagic lesions and aggravated experimental ulcers elicited by aspirin, serotonin or indomethacin. Serotonin thyrotropin releasing hormone Rattus norvegicus