Pub. Date : 2017 May
PMID : 28565807
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Arsenic trioxide increases expression of secreted frizzled-related protein 1 gene and inhibits the WNT/beta-catenin signaling pathway in Jurkat cells. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |
2 | The aim of the present study was to investigate the demethylation effect of arsenic trioxide (As2O3) on the secreted frizzled-related protein 1 (SFRP1) gene and its ability to inhibit the Wingless-type MMTV integration site family (WNT) pathway in Jurkat cells. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |
3 | The aim of the present study was to investigate the demethylation effect of arsenic trioxide (As2O3) on the secreted frizzled-related protein 1 (SFRP1) gene and its ability to inhibit the Wingless-type MMTV integration site family (WNT) pathway in Jurkat cells. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |
4 | The aim of the present study was to investigate the demethylation effect of arsenic trioxide (As2O3) on the secreted frizzled-related protein 1 (SFRP1) gene and its ability to inhibit the Wingless-type MMTV integration site family (WNT) pathway in Jurkat cells. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |
5 | The aim of the present study was to investigate the demethylation effect of arsenic trioxide (As2O3) on the secreted frizzled-related protein 1 (SFRP1) gene and its ability to inhibit the Wingless-type MMTV integration site family (WNT) pathway in Jurkat cells. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |
6 | Following treatment with As2O3 for 48 h, the SFRP1 gene was demethylated, and the mRNA and protein expression levels of the SFRP1 gene were increased. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |
7 | Following treatment with As2O3 for 48 h, the SFRP1 gene was demethylated, and the mRNA and protein expression levels of the SFRP1 gene were increased. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |
8 | These results suggest that As2O3 activates SFRP1 gene expression at the mRNA and protein levels in Jurkat cells by demethylation of the SFRP1 gene. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |
9 | These results suggest that As2O3 activates SFRP1 gene expression at the mRNA and protein levels in Jurkat cells by demethylation of the SFRP1 gene. | Arsenic Trioxide | secreted frizzled related protein 1 | Homo sapiens |