Title : Nickel-induced HIF-1α promotes growth arrest and senescence in normal human cells but lacks toxic effects in transformed cells.

Pub. Date : 2017 Sep 15

PMID : 28552779






1 Functional Relationships(s)
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1 Nickel is a human carcinogen that acts as a hypoxia mimic by activating the transcription factor HIF-1alpha and hypoxia-like transcriptomic responses. Nickel hypoxia inducible factor 1 subunit alpha Homo sapiens