Pub. Date : 2017 Aug
PMID : 28552631
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | As ferroptosis is induced by inhibition of cysteine uptake or inactivation of the lipid repair enzyme glutathione peroxidase 4 (GPX4), the process is favored by chemical or mutational inhibition of the cystine/glutamate antiporter and culminates in the accumulation of reactive oxygen species (ROS) in the form of lipid hydroperoxides. | Lipid Peroxides | glutathione peroxidase 4 | Mus musculus |
| 2 | As ferroptosis is induced by inhibition of cysteine uptake or inactivation of the lipid repair enzyme glutathione peroxidase 4 (GPX4), the process is favored by chemical or mutational inhibition of the cystine/glutamate antiporter and culminates in the accumulation of reactive oxygen species (ROS) in the form of lipid hydroperoxides. | Lipid Peroxides | glutathione peroxidase 4 | Mus musculus |