Pub. Date : 2017 Sep
PMID : 28546421
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Simvastatin or mevastatin significantly suppressed the effects of ox-LDL or TNFalpha Promoter reporter assays and small interfering RNA knockdown revealed that statins inhibit ox-LDL-mediated NLRP3 inflammasome activation via the pregnane X receptor (PXR). | Simvastatin | tumor necrosis factor | Homo sapiens |