Title : Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma.

Pub. Date : 2017

PMID : 28542253






1 Functional Relationships(s)
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1 These results demonstrate that sodium valproate causes increased histone H3 acetylation indicative of HDAC inhibition, which is inversely correlated with a reduction in cell viability. Valproic Acid histone deacetylase 9 Homo sapiens