Title : MicroRNA-92a promotes epithelial-mesenchymal transition through activation of PTEN/PI3K/AKT signaling pathway in non-small cell lung cancer metastasis.

Pub. Date : 2017 Jul

PMID : 28534966






2 Functional Relationships(s)
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1 In addition, miR-92a could activate the PI3K/AKT pathway by inhibiting PTEN expression. mir-92a phosphatase and tensin homolog Homo sapiens
2 Taken together, these results demonstrated that miR-92a induced EMT and regulated cell migration and invasion in the NSCLC cells through regulating PI3K/AKT signaling pathway by targeting PTEN, indicating that miR-92a may be an attractive target and prognostic marker for NSCLC. mir-92a phosphatase and tensin homolog Homo sapiens