Pub. Date : 2017 May
PMID : 28529596
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It was demonstrated that activity of the TRAIL-R2 (DR5) pathway was critical in the development of andrographolide-mediated rhTRAIL sensitization, since its inhibition significantly reduced the extent of apoptosis induced by the combination of rhTRAIL and andrographolide. | andrographolide | TNF receptor superfamily member 10b | Homo sapiens |
| 2 | It was demonstrated that activity of the TRAIL-R2 (DR5) pathway was critical in the development of andrographolide-mediated rhTRAIL sensitization, since its inhibition significantly reduced the extent of apoptosis induced by the combination of rhTRAIL and andrographolide. | andrographolide | TNF receptor superfamily member 10b | Homo sapiens |
| 3 | It was demonstrated that activity of the TRAIL-R2 (DR5) pathway was critical in the development of andrographolide-mediated rhTRAIL sensitization, since its inhibition significantly reduced the extent of apoptosis induced by the combination of rhTRAIL and andrographolide. | andrographolide | TNF receptor superfamily member 10b | Homo sapiens |
| 4 | It was demonstrated that activity of the TRAIL-R2 (DR5) pathway was critical in the development of andrographolide-mediated rhTRAIL sensitization, since its inhibition significantly reduced the extent of apoptosis induced by the combination of rhTRAIL and andrographolide. | andrographolide | TNF receptor superfamily member 10b | Homo sapiens |
| 5 | N-acetyl cysteine prevented andrographolide-mediated DR5 induction and the apoptotic effect induced by the combination of rhTRAIL and andrographolide. | andrographolide | TNF receptor superfamily member 10b | Homo sapiens |
| 6 | Collectively, the present study demonstrated that andrographolide enhances TRAIL-induced apoptosis through induction of DR5 expression. | andrographolide | TNF receptor superfamily member 10b | Homo sapiens |