Title : Immediate and delayed potentiating effects of tumor necrosis factor-α on TRPV1 sensitivity of rat vagal pulmonary sensory neurons.

Pub. Date : 2017 Aug 1

PMID : 28522561






1 Functional Relationships(s)
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1 In conclusion, a brief pretreatment with TNFalpha induced both immediate and delayed potentiating effects on the TRPV1 sensitivity in pulmonary sensory neurons, and the production of COX-2 arachidonic acid metabolites plays a major role in the immediate sensitizing effect of TNFalpha. Arachidonic Acid prostaglandin-endoperoxide synthase 2 Rattus norvegicus