Title : Structure based discovery of clomifene as a potent inhibitor of cancer-associated mutant IDH1.

Pub. Date : 2017 Jul 4

PMID : 28498812






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Isocitrate dehydrogenase (IDH) plays an indispensable role in the tricarboxylic acid cycle, and IDH mutations are present in nearly 75% of glioma and 20% of acute myeloid leukemia. Tricarboxylic Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens
2 Isocitrate dehydrogenase (IDH) plays an indispensable role in the tricarboxylic acid cycle, and IDH mutations are present in nearly 75% of glioma and 20% of acute myeloid leukemia. Tricarboxylic Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens