Title : Size reduction of an ACTH-secreting pituitary macroadenoma in Nelson's syndrome by sodium valproate: effect of withdrawal and re-institution of treatment.

Pub. Date : 1988 Nov

PMID : 2847474






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1 Size reduction of an ACTH-secreting pituitary macroadenoma in Nelson"s syndrome by sodium valproate: effect of withdrawal and re-institution of treatment. Valproic Acid proopiomelanocortin Homo sapiens
2 We describe herein the reduction in the size of an ACTH-secreting pituitary macroadenoma in a patient with Nelson"s syndrome during chronic administration of sodium valproate, and the changes in tumour volume after withdrawal and re-institution of treatment. Valproic Acid proopiomelanocortin Homo sapiens
3 The present report documents for the first time the reduction of tumour size in a patient with an ACTH-secreting macroadenoma by chronic administration of sodium valproate. Valproic Acid proopiomelanocortin Homo sapiens