Title : Neomycin inhibits platelet functions and inositol phospholipid metabolism upon stimulation with thrombin, but not with ionomycin or 12-O-tetradecanoyl-phorbol 13-acetate.

Pub. Date : 1988 Oct 15

PMID : 2846297






1 Functional Relationships(s)
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1 The thrombin-induced enhancement of inositol phospholipid metabolism was strongly inhibited by the presence of neomycin whereas the TPA- or ionomycin-induced increase in inositol [32P]polyphospholipids remained unaffected. Ionomycin coagulation factor II, thrombin Homo sapiens